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Submitted: 20 Aug 2020
Accepted: 10 Oct 2020
ePublished: 29 Oct 2020
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J Prev Epidemiol. 2020;5(2): e21.
doi: 10.34172/jpe.2020.21
  Abstract View: 331
  PDF Download: 216

Original

Evaluating the effect of intradialytic exercise on blood pressure, inflammatory markers and dialysis adequacy

Parvin Soltani 1 ORCID logo, Naser Saeedi 1 * ORCID logo, Navidreza Mashaykhi 2, Alireza Rostami 3, Maryam Tajfar 1

1 Department of Internal Medicine, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran
2 Department of Cardiology, Faculty of Medicine, Arak University of Medical Sciences, Arak, Iran
3 Department of Cardiac Surgery, Faculty of Medicine, Arak University of Medical Science, Arak, Iran
Correspondence to: Naser Saeedi, Email: DR.N.Saeedi@arakmu.ir

Abstract

Introduction: In spite of widely accepted idea that exercise is beneficial in dialysis, it is not easy to incorporate an exercise program into routine clinical practice of these patients.

Objectives: The present study was conducted to evaluate the effects of exercise on hemodialysis patients.

Patients and Methods: In this non-pharmacologic clinical trial, a total of 49 clinically stable hemodialysis patients were enrolled in the study and were randomly allocated into two groups; the intervention group (n=27) and the control group (n=22). The intervention group conducted at least 30 minutes of cycling during each hemodialysis session for six months. Intradialytic blood pressure, high-sensitivity C-reactive protein (hs-CRP) blood levels and dialysis adequacy were estimated before and after dialysis.

Results: At the end of the 6-month study period, a significant reduction in systolic and diastolic blood pressure in all patients of the intervention group (P<0.05) was detected. Although the dialysis quality increased more than 1.2, it was not statistically significant. Moreover hs-CRP was decreased in the exercise group at the end of the study, while these outcomes were not statistically significant too.

Conclusion: Intradialytic exercise can lead to a significant reduction in systolic and diastolic blood pressure in hemodialysis patients. Trial registration: This randomized controlled trial was registered in the Iranian Registry of Clinical Trials (#IRCT2015092324152N1, https://irct.ir/trial/20465, ethical code; ARAKMU.REC.1393.168.1).

Keywords: Dialysis quality, Hypertension, inflammatory mediator CRP, intradialytic exercise, End-stage renal disease, Chronic kidney failure, Hemodialysis
Citation: Soltani P, Saeedi N, Mashaykhi NR, , Rostami AR, Tajfar M. Evaluating the effect of intradialytic exercise on blood pressure, inflammatory markers and dialysis adequacy. J Prev Epidemiol. 2020;5(2):e21. doi: 10.34172/ jpe.2020.21.
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