Submitted: 18 Jan 2020
Accepted: 08 Feb 2020
ePublished: 08 Feb 2020
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J Prev Epidemiol. 2019;4(2): e16.
  Abstract View: 86
  PDF Download: 28

Letter to Editor

Is software method helpful for detection of angiogenesis in breast tissue slides?

Soheila Sayad 1 ORCID logo, Mahshid Panahi 2, Reza Nekouian 3,4 * ORCID logo, Saed Sayad 5

1 Department of Breast Surgery, Firoozgar Clinical Research Development Center, Iran University of Medical Sciences, Tehran, Iran
2 Department of Pathology, Firoozgar Clinical Research Development Center, Iran University of Medical Sciences, Tehran, Iran
3 Pediatric Growth and Development Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
4 Department of Medical Biotechnology, Iran University of Medical Sciences, Tehran, Iran
5 Department of Computer Science, Rutgers University, New Jersey, USA
Correspondence to: Reza Nekouian, Email: nekouian.r@lums.ac.ir

Abstract

Sustained angiogenesis is a hallmark of solid tumors. Nowadays, a lot of studies are conducted to investigate angiogenesis and angiogenic pathways. There are many anticancer agents targeting these pathways. However, there is not a clinical method to detect or quantify angiogenesis. In ImageJ software, color threshold of angiogenesis can be defined. However, this method is not specific for hematoxylin and eosin stained slides.
Keywords: Angiogenesis, Breast cancer, Software model
Citation: Sayad S, Panahi M, Nekouian R, Sayad S. Is software method helpful for detection of angiogenesis in breast tissue slides? J Prev Epidemiol. 2019;4(2):e16.
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