Submitted: 14 Jun 2020
Accepted: 29 Jun 2020
ePublished: 06 Jul 2020
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J Prev Epidemiol. 2020;5(1): e03.
doi: 10.34172/jpe.2020.03
  Abstract View: 396
  PDF Download: 44

Review

Confirmatory and supportive laboratory investigations in SARS-CoV-2 infection; a systematic review

Eranga Harshani Silva 1 * , Sarath Lekamwasam 2

1 Department of Medical Laboratory Science, Faculty of Allied Health Sciences, University of Ruhuna, Galle, Sri Lanka
2 Department of Medicine, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka
Correspondence to: Eranga Harshani Silva, Email: eranga.silva@yahoo. com, ehsilva@ahs.ruh.ac.lk, slekamwasam@gmail.com

Abstract

The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread over 210 countries. In order to mitigate the epidemic and to flatten the curve, apart from multiple containment measures, an accurate identification of those infected is imperative. The objective of this review was to review, systematically, the performance of diagnostic and screening technologies and the yield of different clinical samples for the detection of SARS-CoV-2. Here we have critically evaluated the results obtained from different clinical samples and laboratory investigations and the performance of rRT-PCR (real-time reverse transcriptase polymerase chain reaction) technique in the diagnosis of SARS-CoV-2.
Keywords: COVID-19, SARS-CoV-2, Coronavirus, Confirmatory tests, Supportive tests
Citation: Silva EH, Lekamwasam S. Confirmatory and supportive laboratory investigations in SARSCoV-2 infection; a systematic review. J Prev Epidemiol. 2020;5(1):e03. doi: 10.34172/ jpe.2020.03.
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