Helicobacter pylori (H. pylori) is a very common pathogenic microorganism that colonizes the stomach of about half of all populations. It plays an important role in the gastroduodenal diseases like gastric lymphoma, peptic ulcers, and acute chronic gastritis. Some common antibiotics used for the treatment of H. pylori infection are metronidazole (MTZ), clarithromycin (CLA), amoxicillin and tetracycline. However, recently much attention had been directed toward administration of medicinal plants for the treatment of H. pylori. The use of herbal medicines as a source for new drugs as well as relief from diseases can be traced back over the early civilization. Considering the potentiality of medicinal plants as a source for antimicrobial drugs, the present study was based on the review of such plants to review the published papers about the effects of herbal medicines and medicinal plants against H. pylori infection.