Logo-jpe
Submitted: 29 Sep 2019
Accepted: 10 Nov 2019
ePublished: 18 Dec 2019
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)

J Prev Epidemiol. 2019;4(2): e27.
  Abstract View: 659
  PDF Download: 372

Review

Mechanisms of Helicobacter pylori-induced gastric mucosal injury

Mohammad Bahadoram 1,2, Bijan Keikhaei 2, Mohammad-Reza Mahmoudian-Sani 2, Kosar Alikhani 2, Motahareh Motiee 2, Ammar Helalinasab 2, Maedeh Barahman 1*

1 Department of Radiation Oncology, Firoozgar Hospital, Firoozgar Clinical Research Development Center (FCRDC), Iran University of Medical Sciences (IUMS), Tehran, Iran
2 Thalassemia and Hemoglobinopathy Research Center, Research Institute of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
*Corresponding Author: Correspondence to: Maedeh Barahman, Email: maedeh.barahman@gmail.com, , Email: brahman.m@iums.ac.ir

Abstract

Helicobacter pylori is a common pathogenic microorganism which is able to colonize in harsh acidic environment of the stomach. It also plays an important role in developing gastric cancer (GC) by causing inflammation, epigenetic changes in cancer-related genes, and disturbance in life cycle of cells. Besides, GC is the fourth most common cause of cancer-related mortality in the world. There is still no consensus regarding the eradication of H. pylori and its effects in terms of preventing gastric lesion or atrophy progression. The main purpose of this review was to evaluate factors shaping H. pylori colonization into gastric epithelial cells and then normal gastric mucosa progression to GC.

Citation: Bahadoram M, Keikhaei B, Mahmoudian-Sani MR, Alikhani K, Motiee M, Helalinasab A, Barahman M. Mechanisms of Helicobacter pyloriinduced gastric mucosal injury. J Prev Epidemiol. 2019;4(2):e27.
First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 660

Your browser does not support the canvas element.


PDF Download: 372

Your browser does not support the canvas element.