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Submitted: 20 Apr 2021
Accepted: 01 Jun 2021
ePublished: 10 Jun 2021
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J Prev Epidemiol. 2021;6(2): e24.
doi: 10.34172/jpe.2021.24
  Abstract View: 59
  PDF Download: 37

Original

COVID-19 infection and beta thalassemia; a single center experience in Iran

Roya Salehi Kahyesh 1 ORCID logo, Arash Alghasi 1* ORCID logo, Bijan Keikhaei Dehdezi 1 ORCID logo, Adeleh Khazami 2 ORCID logo, Marzeieh Abbasi Nasab 1 ORCID logo

1 Thalassemia and Hemoglobinopathies Research centre, research institute of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Baqaei2 hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Correspondence to: Arash Alghasi , Email; arashalqasi@yahoo.com, alghasi-a@ajums.ac.ir

Abstract

Introduction: COVID-19 infection is a contagious acute respiratory syndrome, leading to a high mortality rate; it is also a systemic disease, and all people are at risk of being infected, including hemoglobinopathies patients. Thalassemia is one of the most prevalent hemoglobinopathies while Beta-thalassemia patients, are at risk for the deadly effects of the coronavirus.

Objectives: This study examines the prevalence, severity, and mortality rate of COVID-19 infection in thalassemia patients of the southwest of Iran.

Patients and Methods: In this descriptive cross-sectional study, from March 2019 to September 2020, 1000 beta-thalassemia patients, referred to Shahid Baqaei 2 hospital, Ahvaz, Iran, were screened for COVID-19.

Results: Findings showwd 80% of thalassemia patients were women. Fever, body aches, weakness, and dizziness were the main symptoms of patients.

Conclusion: This result suggests that hemoglobinopathies may affect infections and mortality from COVID-19 infection. However, our findings do not support a direct association between hemoglobin disease and COVID-19, and further research is needed to confirm this, but this might state the hemoglobin’s role in the pathophysiology of COVID-19 infection.


Keywords: Hemoglobinopathy, COVID-19, Beta thalassemia
Citation: Salehi Kahyesh R, Alqasi A, Keikhaei Dehdezi B, Khazami A, Abbasi Nasab M. COVID-19 infection and beta thalassemia; a single center experience in Iran. J Prev Epidemiol. 2021;6(2):e24. doi: 10.34172/jpe.2021.24.
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