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Submitted: 13 Jan 2021
Accepted: 03 Mar 2021
ePublished: 01 Jul 2021
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J Prev Epidemiol. 2021;6(1): e05.
doi: 10.34172/jpe.2021.05
  Abstract View: 557
  PDF Download: 589

Original

Effectiveness of neonatal screening for congenital hypothyroidism

Behrouz Shayestefard 1 ORCID logo, Naim Sadat Kia 2 ORCID logo, Masoumeh Alimohammadi 3 ORCID logo, Elaheh Ghods 4* ORCID logo

1 Medical student, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran
2 Community Medicine Specialist, Social Determinant of Health Research Center, Community and Family Health Department, Semnan University of Medical Sciences, Semnan, Iran
3 Islamic Azad University, Department of Psychology, Shahrood Branch., Islamic Azad University, Semnan, Iran
4 Social Determinant of Health Research Center, Community and Family Health Department, Semnan University of Medical Sciences, Semnan, Iran
*Corresponding Author: Correspondence to: Elaheh Ghods, ghodsemla@ yahoo.com, , Email: elaheghods@ semums.ac.ir

Abstract

Introduction: Congenital hypothyroidism (CH) is the most common preventable cause of mental retardation. Newborn screening program considerably increases probability of CH diagnosis and treatment.

Objectives: We aimed to investigate the efficacy of running CH screening program to maintain normal IQ and physical growth of hypothyroid children in Semnan city.

Patients and Methods: This study was performed on children with definite CH who were treated and followed up in Semnan health centers. Around 41 children born within 2008-2013 (minimum three years of age) participated. Respective weight and height for age were measured. The Z-scores were calculated based on the WHO-Anthro-Anthro Plus Software. Intelligence Quotient (IQ) was measured with Wechsler Intelligence Score for children-revised (WISC-R). Data analyzed with one-tailed t test compared with age and gender-matched group.

Results: The mean IQ Score in our study group was 90.09 (1.73) with no significant difference compared to healthy counterparts (P > 0.05). Z-score for weight and height was -0.46 and -0.45 prospectively and was not significantly different from normal children.

Conclusion: Newborn screening program for CH has been effective in preventing mental retardation and growth failure.


Citation: Behrouz S, Kia NS, Alimohammadi M, Ghods E. Effectiveness of neonatal screening for congenital hypothyroidism. J Prev Epidemiol. 2021;6(1):e05. doi: 10.34172/ jpe.2021.05.
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