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Submitted: 21 Jul 2021
Accepted: 14 Oct 2021
ePublished: 25 Oct 2021
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J Prev Epidemiol. 2022;7(1): e03.
doi: 10.34172/jpe.2022.03
  Abstract View: 1462
  PDF Download: 705

Review

A review of the reasons for high prevalence and rapid progression of COVID-19 in men

Neda Taghizabet 1 ORCID logo, Fatemeh Rezaei-Tazangi 2* ORCID logo, Hossein Roghani‐Shahraki 3 ORCID logo

1 Department of Anatomical Sciences, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2 Department of Anatomical Sciences, Faculty of Medicine, Fasa University of Medical Sciences, Fasa, Iran
3 Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
*Corresponding Author: Correspondence to: Fatemeh Rezaei-Tazangi, Email: f.rezaei67@yahoo.com, , Email: f.rezaei@ fums.ac.ir

Abstract

Previous studies have demonstrated a relationship between gender and COVID-19 outcomes. In addition, this is confirmed that men have more danger of progressing an acute type of the illness than women, specifies the significance of miscellaneous data related to male and female patients with COVID-19. In other words, some factors like hormonal levels and immune function may interact with each other. A perception of the fundamental reasons for gender diversities in COVID-19 patients can beget a chance for disease prevention and faster treatment. The present study evaluates the role of gender in the incidence and progression of the COVID-19 disease. It has been explained that how gender affects angiotensin-converting enzyme 2 (ACE2), which is a basic factor for the COVID-19 pathogenesis introducing the sex diversities in platelet function, immune reactions and how sex hormones affect immune functions, also the effect of androgens on transmembrane protein serine protease 2 (TMPRSS2) receptor in COVID-19 patients was investigated.

Citation: Taghizabet N, Rezaei-Tazangi F, Roghani-Shahraki H. A review of the reasons for high prevalence and rapid progression of COVID-19 in men. J Prev Epidemiol. 2022;7(1):e03. doi: 10.34172/jpe.2022.03.
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