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Submitted: 11 Nov 2020
Accepted: 03 Dec 2020
ePublished: 20 Dec 2020
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J Prev Epidemiol. 2020;5(2): e34.
doi: 10.34172/jpe.2020.34
  Abstract View: 422
  PDF Download: 319

Review

The relationship between serum vitamin D level and COVID-19; a review study

Yasaman Koohshoori 1 ORCID logo, Ehsan Ramanian 2, Nasrin Moradi 3, Shahrzad Shadabi 4, Minoo Motahhar 5, Masoumeh Sadat Mousavi 6,7*, Mahmood Banoore 8

1 Department of Epidemiology and Biostatistics, School of Public Health, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 MD Fellowship of Rheumatology, Tehran University of Medical Sciences, Tehran, Iran
3 PhD Student, School of Medical Management and Information, Iran University of Medical Sciences, Tehran, Iran
4 Department of Medical Virology, Kerman University of Medical Sciences, Kerman, Iran
5 Department of Pathobiology, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran
6 Modeling in Health Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran
7 Department of Epidemiology and Biostatistics, School of Public Health, Shahrekord University of Medical Sciences, Shahrekord, Iran
8 Emergency Medical Specialist, Isfahan University of Medical Sciences, Isfahan, Iran
*Corresponding Author: Correspondence to: Masoumeh Sadat Mousavi, Email: mousavi68.ma@yahoo. com, , Email: ma@skuns.ac.ir

Abstract

Introduction: Coronavirus disease 2019 (COVID-19) from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is one of the most important epidemiological events in the past 100 years has become, the consequences for public health and economic systems around the world. Vitamin D is an important micronutrient that has been reported to improve immunity and protect against respiratory diseases. In this study, we intend to review articles that examine the relationship between COVID-19 and vitamin D.

Methods: This is a review that uses articles from studies published in 2020 on the relationship between COVID-19 and vitamin D in databases such as; Web of Science, Science Direct, SID, Magiran, Google Scholar and PubMed. Keywords used included; serum levels of 25-hydroxyvitamin D, vitamin D, COVID-19, SARS-COV-2 and coronavirus 2. With this search, 32 articles were finally selected for this purpose and their results were reviewed

Results: Of the 32 studies reviewed, only three showed no association between vitamin D levels in the blood and COVID-19 disease. Other studies had a relationship between the severity of the disease, mortality rate and length of hospital stay, in different age, gender and location groups.

Conclusion: It seems that the level of vitamin D in the blood has a potential effect on COVID-19 disease. Checking the serum vitamin D levels and supplementation in people with hypovitaminosis D can be a good solution to reduce the complications and problems caused by COVID-19.



Citation: Koohshoori Y, Ramanian E, Moradi N, Shadabi S, Motahhar M, Mousavi MS, Banoore M. The relationship between serum vitamin D level and COVID-19; a review study. J Prev Epidemiol. 2020;5(2):e34. doi: 10.34172/jpe.2020.34.
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