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Submitted: 09 Sep 2022
Accepted: 14 Jan 2023
ePublished: 18 Feb 2023
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J Prev Epidemiol. 2023;8(1): e26181.
doi: 10.34172/jpe.2023.26181
  Abstract View: 718
  PDF Download: 343

Original Article

Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study

Naser Aslanabadi 1 ORCID logo, Nader Jangioskouei 2 ORCID logo, Negar Jafari 2 ORCID logo, Azin Pakmehr 3 ORCID logo, Amirreza Khalaji 3 ORCID logo, Azam Esmailnejad 2 ORCID logo, Mohammadreza Moslemi 4* ORCID logo, Shahin Khabbazi 5

1 Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
2 Department of Cardiovascular Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
3 Department of Internal Medicine, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
4 Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
5 Urmia University of Medical Sciences, Urmia, Iran
*Corresponding Author: Mohammadreza Moslemi, Email: moslemi_mohammadreza@yahoo.com

Abstract

Introduction: Coronary artery diseases (CADs) are a global health issue. In addition, several researchers have reported a correlation between serum vitamin D levels and different aspects of cardiovascular diseases. It has been reported that vitamin D can modulate atherothrombosis.

Objectives: This study aimed to investigate the correlation between 25-hydroxyvitamin D and CAD severity.

Patients and Methods: This is a cross-sectional study. The study sample consisted of patients undergoing elective coronary angiography. To assess 25-hydroxyvitamin D levels, fasting samples were collected from patients. Patients were included in this study based on the number of involved coronary vessels and SYNTAX classification.

Results: The serum levels of 25-hydroxyvitamin D were significantly lower in the group of patients with CAD and cardiovascular disease than in the control group (P<0.001). This study showed, severe vitamin D deficiency caused significantly higher SYNTAX scores (P<0.001).

Conclusion: The results of our study showed, vitamin D deficiency might have an essential relationship with the severity and incidence of CAD; however, we recommend further studies to investigate the preventing effects of vitamin D supplementation, primarily through intervention studies.


Citation: Aslanabadi N, Jangioskouei N, Jafari N, Pakmehr A, Khalaji A, Esmailnejad A, Moslemi M, Khabbazi S. Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study. J Prev Epidemiol. 2023;8(1):e26181. doi: 10.34172/ jpe.2023.26181.
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