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Submitted: 20 May 2023
Accepted: 17 Jul 2023
ePublished: 03 Aug 2023
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J Prev Epidemiol. 2023;8(2): e35223.
doi: 10.34172/jpe.2023.35223
  Abstract View: 181
  PDF Download: 56

Mini Review

Collapsing glomerulopathy following COVID 19 infection; a mini-review to the recent data

Leila Alem 1 ORCID logo, Maryam Farahmandsadr 2 ORCID logo, Azadeh Khayyat 3 ORCID logo, Mohammad Ali Esmaeil Pour 4 ORCID logo, Hamid Nasri 1* ORCID logo

1 Nickan Research Institute, Isfahan, Iran
2 Researcher, 64 Commonwealth Rd, Watertown, MA, USA
3 Pathology Department of Medical College of Wisconsin, Milwaukee, WI, USA
4 Internal Medicine Department of UNC Health Blue Ridge, Morganton, NC, USA
*Corresponding Author: Prof. Hamid Nasri, Email: hamidnasri@med.mui.ac.ir, , Email: hamidnasri@yahoo.com

Abstract

Collapsing glomerulopathy has been delineated as the most common morphological feature in COVID-19 individuals presenting with rapidly progressive renal failure and massive proteinuria. This condition, also known as COVID-19-associated nephropathy, has a poor prognosis. In COVID-19-related collapsing glomerulopathy, an immune dysfunction-mediated “second hit” to podocytes of African origin with APOL1 risk alleles was suggested. However, further research is still required to clarify this aspect of glomerulopathy.

Citation: Alem L, Farahmandsadr M, Khayyat A, Esmaeil pour MA, Nasri H. Collapsing glomerulopathy following COVID 19 infection; a mini-review to the recent data. J Prev Epidemiol. 2023;8(2):e35223. doi: 10.34172/ jpe.2023.35223.
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