Abstract
Introduction: Autoimmune thyroid disease (AITD) including Hashimoto’s thyroiditis (HT) and Grave’s disease (GD) is a common immune-mediated disease. It has an association with the increased incidence of other autoimmune diseases.
Objectives: The purpose of the current study was to describe the prevalence and distribution of non-thyroidal immune-mediated disease in patients with AITD.
Patients and Methods: This study was a retrospective. All patients who were diagnosed with AITD in their thyroid biopsy were enrolled. The information about the coexisting disease was obtained by a trained physician using a questionnaire. The confirmed data about the disease in six systems were documented in the questionnaire
Results: Of 293 AITD patients, 250 eligible cases with an average age of 48.7 years old including 23 male patients and 227 female patients were included in the study. We found 224 patients did not have a coexisting autoimmune disease. The 26 remaining patients were; 17 patients with skin disease, 3 patients with rheumatologic disease, 3 patients with endocrine disease and 2 patients with hematologic disease and none of the patients had neurologic disease. The prevalence of the disease increased with age and had no relation to gender.
Conclusion: Our study showed the prevalence of non-thyroidal immune-mediated disease increased in AITD patients. Autoimmune skin disorders are the most common disease in these patients, followed by rheumatologic and endocrine diseases.