Fatemeh Dehghan Shahreza
1*1 Department of Clinical Science, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran
Abstract
Endothelial cells play critical role in maintenance of vascular hemostasis through endothelialderived nitric oxide (EDNO) regulated processes. Several abnormalities contribute in blood flow disturbance by triggering oxidative stress interrupted nitric oxide metabolism. It is known various natural bioactive compounds that can alter endothelial signaling pathways to survive cells under stress state abnormalities.