Hereditary hemochromatosis is a disease associated with highly iron overload. This disease caused by
genetic mutations inherited through family. Autoimmune hemolytic anemia is also an important autoimmune
disease in which red blood cells (RBC) are destroyed mostly in spleen, extravascular hemolysis, and is
related to secondary hemochromatosis. Here in this report, we report a 42-year-old woman diagnosed and
treated as resistant autoimmune hemolytic anemia for almost 8 years and then diagnosed with hereditary
hemochromatosis caused by HFE gene mutation (C282Y homozygous genotype). We suggest that in steroid
dependent autoimmune hemolytic anemia cases, serum iron and ferritin measurements should be conducted
regularly and a possible diagnosis of hereditary hemochromatosis or secondary hemochromatosis should be
considered even if no familial history is existed.
Citation: Falahatian M,
Khosravi Farsani MR,
Hajigholami A. Hereditary
anemia; A case report.
J Prev Epidemiol.