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Submitted: 07 Dec 2021
Accepted: 15 Feb 2022
ePublished: 03 Mar 2022
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  Abstract View: 469

Original

Evaluation of the influential factors on the mortality of patients with acute myocardial infarction

Adalat Hoseinian 1 ORCID logo, Mohammad Bahadoram 2 ORCID logo, Firouz Amani 3* ORCID logo, Sajjad Hakimian 4, Saba Attar-Madraki 5, Raana Jafarizadeh 6 ORCID logo

1 Department of Internal Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
2 Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
3 Department of Community Medicine, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
4 School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
5 Department of Biomedical Engineering, Tabriz Azad University, Tabriz, Iran
6 Department of Medicine, Ardabil Branch, Islamic Azad University, Ardabil, Iran
Correspondence to: Firouz Amani, Email: biostat.f@ gmail.com, firouz.amani@arums. ac.ir

Abstract

Introduction: Death caused by myocardial infarction (MI) usually occurs during the first hours after the onset of symptoms. Therefore, to manage, treat and decrease the mortality rate of these patients, early hospital admission is important.

Objectives: We aimed to investigate the impact of the influential factors on mortality of patients with MI.

Patients and Methods: In this case-control study, MI patients who were referred to the Ardabil Alavi Hospital, Ardabil university of medical sciences, Ardabil, Iran between April 2017 and April 2018 were included. The patients that had died due to MI were considered as the case group (n=27) and 27 matched patients that had died due to other causes were selected as the control group. Linear logistic regression was employed to analyze the data.

Results: The mean age of the patients in the case group was significantly higher than in the control group (75.1±11.7 versus 63.;1±11.6, P=0.001). The history of non-cardiac diseases in the case group (44.4%) was significantly higher than in the control group (7.4%; P=0.002). The number of PCIs (percutaneous coronary interventions) that were conducted in the case group (40.7%) was significantly lower than in the control group (74.1%; p=0.013). The time distance between hospital admission and PCI performance in the case group (110.9 minutes) was significantly higher than in the control group (56 minutes; P=0.001). However, the mean of delay time from the onset of symptoms to hospital admission (the patient delay) and from hospital admission to receiving treatment (the health system delay) was similar between the two groups.

Conclusion: This study showed that the number of performed PCIs, history of non-cardiac disorders and the interval between the onset of symptoms and PCI performance are significantly associated with the morality of MI patients.


Keywords: Acute myocardial infarction, Mortality, Hospital admission delay
Citation: Hoseinian A, Bahadoram M , Amani F, Hakimian S, Attar-Madraki S, Jafarizadeh R. Evaluation of the influential factors on the mortality of patients with acute myocardial infarction . J Prev Epidemiol. 2022;7(2):exx. doi: 10.34172/jpe.2022. xx.
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