Society of Diabetic Nephropathy Prevention Journal of Preventive Epidemiology 2476-3934 5 2 2020 07 01 Prevalence of biologic, behavioral and psychosocial determinant of tuberculosis in tuberculosis patients of Semnan city; a five-year cross-sectional study e24 e24 10.34172/jpe.2020.24 EN Naim Sadat Kia https://orcid.org/0000-0002-6003-0741 Mohammad Nassaji Zavareh https://orcid.org/0000-0003-0821-5324 Elnaz Sarkheil https://orcid.org/0000-0002-7716-1051 Elaheh Ghods https://orcid.org/0000-0001-8254-1983 Journal Article 10.34172/jpe.2020.24 2020 08 15 2020 11 23 Introduction: Tuberculosis (TB) is one of the most common and lethal infectious diseases. Objectives: Due to the impact of biological, behavioral, socio-economic factors on the incidence of TB and the risks of the disease, we aimed to investigate the factors affecting TB in TB patients in Semnan. Patients and Methods: All patients with confirmed TB, who were referred to primary healthcare centers in Semnan for receiving medication, enrolled in the study (2012 to 2016). Data collected from clinical records and in-person interviews. The questionnaire consisted of two parts; the first part was demographic data and the other was related to the risk factors for TB. Results: The household crowding index was 1.86 ± 0.88. Most of patients (48.1%) were elderly (≥60 years old), female (59.7%), housewife (48.1%), had a pre-diploma education (63.6%), low-monthly income (62.3%) and married (63.6%). Around13.0% had diabetes. 20.8% drug abuser, 16.9% cigarettes and tobacco smokers, and 1.3% consumed alcoholic beverages. Besides, 40.3% were Afghans and 1.3% had the Pakistani nation. Conclusion: Identifying and controlling the social, geographical and biological factors affecting the incidence and mortality of TB in different regions can help to formulate appropriate strategies for achieving global goals. These factors differ among native and non-native population.