Society of Diabetic Nephropathy Prevention Journal of Preventive Epidemiology 2476-3934 5 1 2020 01 01 Confirmatory and supportive laboratory investigations in SARS-CoV-2 infection; a systematic review e03 e03 10.34172/jpe.2020.03 EN Eranga Harshani Silva Sarath Lekamwasam Journal Article 10.34172/jpe.2020.03 2020 06 14 2020 06 29 The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread over 210 countries. In order to mitigate the epidemic and to flatten the curve, apart from multiple containment measures, an accurate identification of those infected is imperative. The objective of this review was to review, systematically, the performance of diagnostic and screening technologies and the yield of different clinical samples for the detection of SARS-CoV-2. Here we have critically evaluated the results obtained from different clinical samples and laboratory investigations and the performance of rRT-PCR (real-time reverse transcriptase polymerase chain reaction) technique in the diagnosis of SARS-CoV-2.